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Emerging Pathogens of Dermatological Interest

Francesco Drago, MD; Alfredo Rebora, MD

Arch Dermatol. 1999;135:71-75.

Objectives  To discuss the current knowledge of 3 recently discovered human herpesviruses (HHV-6, HHV-7, and HHV-8), and to provide a dermatological point of view.

Data Sources  References identified from bibliographies of pertinent articles in the English language.

Study Selection and Data Extraction  Articles were selected according to their impact factor and the interest for dermatologists.

Data Synthesis  As the other members of the family Herpesviridae, HHV-6, HHV-7, and HHV-8 may cause a primary infection, establish latent infection in a specific set of cells of their host, and then reactivate if conditions of altered immunity develop. The main pathological conditions associated with them are discussed.

Conclusions  Human herpesvirus 6, HHV-7, and HHV-8 have provided new insights in some dermatological diseases. Although new studies are needed, they may have a profound impact on dermatology in the years to come.

From the Department of Dermatology, University of Genoa, Genoa, Italy.

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