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Methicillin-Resistant Staphylococcus aureus Nosocomial Acquisition and Carrier State in a Wound Care Center
Guillaume Kac, MD;
Annie Buu-Hoï, MD;
Elisabeth Hérisson, RN;
Patricia Biancardini, RN;
Clélia Debure, MD
Arch Dermatol. 2000;136:735-739.
Objective To assess methicillin-resistant Staphylococcus aureus (MRSA) nosocomial acquisition and carrier state in a wound care center.
Design and Setting The results of an intervention to control MRSA were compared with those of historical controls at the wound care center of university-based Hôpital Broussais, Paris, France.
Patients Patients admitted for specific care of chronic ulcers and surgical wounds.
Main Outcome Measures Incidence rates of MRSA carriers and acquisition in wounds.
Results Of 88 patients admitted during a 3-month preintervention period in 1993, 18 (21%) were MRSA carriers. Of 334 patients admitted in 1994 and 395 in 1996, 65 (19.5%) and 81 (20.5%) were MRSA carriers, respectively (P=.80). In 1993, 6 (9%) of 70 patients without MRSA acquired MRSA wound infections; the corresponding numbers were 6 (2.2%) of 269 in 1994 and 3 (0.9%) of 314 in 1996. Despite that the number of MRSA carriers remained stable at admission to the wound care center, the rate of MRSA infections in wounds per 100 noncarriers decreased significantly between the preintervention period and subsequent years: 1994 (P=.02) and 1996 (P=.002).
Conclusions Although our results are limited by the use of historical controls, they showed that simple infection control measures, such as the use of soap and water and barrier precautions associated with staff education, seemed to significantly reduce MRSA infection rates in patients with chronic skin breaks.
From the Unité d'Hygiène (Dr Kac and Ms Hérisson), Laboratoire de Microbiologie (Dr Buu-Hoï), and Service de Rééducation Vasculaire (Ms Biancardini and Dr Debure), Hôpital Broussais, Paris, France.
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