Background Pyogenic granuloma is a frequently diagnosed, benign vascular lesion.
Objectives To present the use of the combined continuous-wave/pulsed carbon dioxide
(CO2) laser as an innovative therapeutic method, to compare it
with established methods, and to assess its results.
Design Prospective observational study between March 1998 and July 2000, comprising
1 treatment session with 6-week and 6-month follow-up examinations and evaluations.
Setting Private or institutional practices as well as ambulatory or hospitalized
care.
Patients One hundred patients with pyogenic granuloma selected from a population-based
sample.
Interventions Treatment with CO2 laser. The laser was first used in continuous
mode (power, 15 W) and then in pulsed mode (pulse length, 0.6-0.9 milliseconds;
energy fluence, 500 mJ/pulse).
Main Outcome Measure Complete resolution of treated granuloma pyogenicum.
Results Pyogenic granuloma was removed completely in 1 treatment session in
98 patients without recurrence. In 88 cases there were no visible scars; in
10 cases slight textural changes of the skin were observed. Hypertrophic scars
or keloids did not occur. Sixty-three patients were very satisfied with the
result of the treatment, 37 were satisfied (ie, 100% patient satisfaction),
and none indicated that they were not satisfied. No permanent hypopigmentation,
hyperpigmentation, or erythema was observed.
Conclusions The combined continuous-wave/pulsed CO2 laser is our treatment
of choice for pyogenic granuloma because this kind of laser is widely available,
produces excellent results with few adverse effects, is easy to use, yields
low recurrence rates, and is well tolerated by most patients.
