This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Dermatologic Disorders  • Neoplasms  • Diagnosis  • Psoriasis  • Dermatologic Disorders, Other  • Alert me on articles by topic  Social Bookmarking   What's this?

Roger H. Weenig, MD; Nneka I. Comfere, MD; Lawrence E. Gibson, MD; Javier Alonso-Llamazares, MD, PhD; Mark D. P. Davis, MD; Mark R. Pittelkow, MD; Rokea A. el-Azhary, MD, PhD

Arch Dermatol. 2009;145(7):801-808.

Background  Psoriasis is a common, nonulcerative skin disorder.

Observations  We describe 3 men recently referred to our institution for evaluation and treatment of severe, ulcerative psoriasis that ultimately was determined to be aggressive, cytotoxic, cutaneous lymphoma. Each had a history of relatively indolent, nonulcerative patches and plaques (duration, 2-45 years) that changed to ulcerated lesions; these rapidly progressed and eventuated in death.

Conclusions  The clinical characteristics of the skin lesions and the histopathologic findings form a distinct and rare presentation of cutaneous lymphoma. The initial course is similar to that of mycosis fungoides but eventuates in a highly aggressive disease with fatal outcome.

Author Affiliations: Department of Dermatology, Mayo Clinic, Rochester, Minnesota.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLES

This Month in Archives of Dermatology
Arch Dermatol. 2009;145(7):745.
FULL TEXT  

On the Trail of a New Killer
Joan Guitart and Gary S. Wood
Arch Dermatol. 2009;145(7):811-813.
EXTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

On the Trail of a New Killer
Guitart and Wood
Arch Dermatol 2009;145:811-813.
FULL TEXT