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  Vol. 86 No. 5, November 1962 TABLE OF CONTENTS
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Toxic Epidermal Necrolysis

MARTIN BEARE, M.D., M.R.C.P.

Arch Dermatol. 1962;86(5):638-653.


Abstract

Ten new cases of toxic epidermal necrolysis are recorded.

The series includes several young babies; I was aged only 2 weeks, and 3 children were under the age of I month.

One child had a second attack, and this was dramatically stopped by early administration of steroids.

One adult patient was seen, and after she became profoundly ill much hypertrophic scarring was left on several scattered areas.

The adult patient was given very large daily doses of steroid drugs about the third month of pregnancy. She eventually gave birth to a normal child after 37 weeks' pregnancy.

The most striking feature in all cases was pain and skin tenderness.

In most of the 10 cases the hairy parts of the body were not affected.

In only one case was drug sensitivity considered the likely cause. In several of the patients no drugs at all had ever been given.



Author Affiliations

BELFAST, NORTHERN IRELAND

Consultant Dermatologist to the Royal Victoria Hospital and the Royal Belfast Hospital for Sick Children.


Footnotes

Read at the Twentieth Annual Meeting of the American Academy of Dermatology and Syphilology, Chicago, 1961.



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