
Sézary's ReticulosisIts Relationship with Neoplasias of the Lymphoreticular System
RAUL FLEISCHMAJER, MD;
SELIG EISENBERG, MD
Arch Dermatol. 1964;89(1):9-19.
Abstract
Two cases of erythroderma, superficial lymphadenopathy, and abnormal circulating cells similar to Sézary's cells are reported. Skin biopsies of infiltrated lesions in both cases showed the picture of mycosis fungoides. One case regarded as an instance of Sézary's reticulosis eventually revealed a malignant lymphoma, Hodgkin's type, of the lymph nodes, although hematological studies suggested a chronic lymphatic leukemia. Further skin biopsies revealed the picture seen in the tumoral stage of mycosis fungoides or in a reticulum cell lymphoma. The second case had large numbers of monocytoid cells in the blood, and a reticulum cell lymphoma of the lymph nodes. The blood picture was also compatible with the diagnosis of monocytic leukemia.
It is suggested that Sézary's reticulosis may not represent a distinct entity, but a syndrome which may be found associated with various neoplastic processes of the lymphoreticular system. The literature on Sézary's reticulosis is reviewed.
Author Affiliations
PHILADELPHIA; NEW YORK
From the Department of Dermatology of the New York University Post-Graduate Medical School and the Service of Dermatology and Syphilology of Bellevue Hospital.
CiteULike Connotea Del.icio.us Digg Reddit Technorati Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Sezary Syndrome: A Clinicopathologic Study of 39 Cases
Buechner and Winkelmann
Arch Dermatol 1983;119:979-986.
ABSTRACT
Mycosis Fungoides of: Prolonged Duration in Siblings
Sandbank and Katzenellenbogen
Arch Dermatol 1968;98:620-627.
ABSTRACT
Sezary Syndrome: A Malignant Leukemic Reticuloendotheliosis
TEDESCHI and LANSINGER
Arch Dermatol 1965;92:257-262.
ABSTRACT
|