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Multiple KeratoacanthomasA Case Study of the Eruptive Type With Observations on Pathogenesis
ROBERT E. ROSSMAN, MD;
ROBERT G. FREEMAN, MD;
JOHN M. KNOX, MD
Arch Dermatol. 1964;89(3):374-381.
Abstract
A case report of a 47-year-old Negro woman with the rare eruptive variant of multiple keratoacanthomas is presented. Unusual features in addition to the vast number of active lesions include their development on palmar and plantar surfaces as well as in her larynx. Keratoacanthomas in all stages were studied and the histopathogenesis discussed. Attempts to isolate a causative virus and induce new lesions with ultraviolet light were unsuccessful. Treatment with systemic cytotoxic agents, including aminopterin and methotrexate, resulted in a minimal and transitory response.
Author Affiliations
HOUSTON, TEX
From the Department of Dermatology and Pathology, Baylor University College of Medicine.
Footnotes
Read before Section on Dermatology at the 112th Annual Meeting of the American Medical Association, Atlantic City, June 16-20, 1963.
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