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ARTHUR B. KERN, MD; BENCEL L. SCHIFF, MD

Arch Dermatol. 1964;89(6):844-845.

Abstract
Prevention of recurrent herpes simplex, despite numerous recommended procedures, has remained a problem. In one of our previous studies, inoculation with a nonspecific vaccine gave results no better than those with the same vaccine which had been heatinactivated. It appeared possible that a specific vaccine might produce greater benefit. A double-blind study has recently been conducted in which one group of patients with recurrent herpes simplex received a series of injections of a specific herpes virus vaccine while the control group was given a placebo solution. No significant difference between the results in the two groups was obtained. It is concluded that the benefit observed is attributable to psychotherapeutic effects.

Author Affiliations
PROVIDENCE, RI; PAWTUCKET, RI

Assistant Clinical Professor of Dermatology, Boston University School of Medicine, Boston University Medical Center (Dr. Kern and Dr. Schiff).

Footnotes
This investigation was supported by a grant from The Lilly Research Laboratories.

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