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A Report of Two New Cases in Sisters

M. H. SAMITZ, MD; DONALD S. WALDORF, MD; JOSEPH SHRAGER, MD

Arch Dermatol. 1964;90(6):567-571.

Abstract
Two additional patients with thalassemia minor and ankle ulcers are reported, bringing the total number reported to ten.

A genealogic study of the thalassemic trait in their family was traced. From a review of the literature it appears that all previous patients with thalassemia and leg ulcers had thalassemia minor. The composite affected patient is a 26-year-old Italian-decended woman with splenomegaly and a hemoglobin of about 8 gm/100 ml.

The pathogenesis of the ulcers is nonspecific.

Treatment is that of a stasis ulcer.

Author Affiliations
PHILADELPHIA

From the Department of Dermatology, School of Medicine, University of Pennsylvania.

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