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RICHARD A. WALZER, MD; JULIA M. EINBINDER, MS; CARL T. NELSON, MD

Arch Dermatol. 1964;90(6):583-587.

Abstract
Immunization of adult rabbits with fetal rabbit skin was not accomplished by the methods described in this study. However, fetal rabbit skin is antigenic when introduced into a heterologous species, as evidenced by the development of non-organ-specific anaphylactic sensitivity in seven of nine animals studied. On the basis of reported studies with other tissues, it is possible that heterologous skin will be an effective antigenic stimulus to the production of antiskin antibodies.

Author Affiliations
NEW YORK

From the Department of Dermatology, College of Physicians and Surgeons, Columbia University.

Footnotes
This investigation was supported by Public Health Service Research grant AM 07241-01 from the National Institute of Allergy and Infectious Diseases.

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Development of Antibodies in Response to Immunization With Heterologous Skin
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ABSTRACT