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R. B. STOUGHTON, MD

Arch Dermatol. 1965;91(6):657-660.

Abstract
Within a few minutes after application to the surface of human skin, hydrocortisone and fluocinolone acetonide in the presence of dimethylsulfoxide (DMSO) are established in a protected reservoir in the stratum corneum. This reservoir remains over a 16 day period and is resistant to washing of the skin surface with soap, water, and alcohol.

Author Affiliations
CLEVELAND

Director of Dermatology-Western Reserve University.

Footnotes
Accepted for publication Dec 29, 1964.

Reprint requests to 2065 Adelbert Road, Lakeside Hospital, Section of Dermatology, Cleveland, Ohio, 44106.

Supported by Armed Forces Epidemiology Board-Commission on Cutaneous Disease.

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