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PHILIP C. ANDERSON, MD; J. M. MARTT, MD

Arch Dermatol. 1965;92(2):181-183.

Abstract
A new inhibitor of cholesterol synthesis, 20,25 diazachlestenol, produced myotonia in 31 persons; and, in six of these, a keratoderma which resembles the natural disease, keratoderma climactericum. These observations further emphasize the importance of normal lipid synthesis in orderly cornification.

Author Affiliations
COLUMBIA, MO

From the Division of Dermatology and Cardiovascular Laboratory, University of Missouri Medical School, Columbia.

Footnotes
Accepted for publication March 31, 1965.

Reprint requests to Division of Dermatology, University of Missouri Medical School, Columbia, Mo (Dr. Anderson).

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