This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (8)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

PHILIP J. LoPRESTI, MD; GEORGE W. HAMBRICK, JR., MD

Arch Dermatol. 1965;92(2):188-191.

Abstract
Zirconium granuloma of the skin, initially seen following the use of zirconium deodorants, continues to occur secondary to the treatment of plant dermatitis with compounds containing zirconium. In our patient the reaction appeared eight weeks after initial use of the agent and has persisted for 18 months without therapy. Intradermal injection of minute amounts of a soluble zirconium compound resulted in production of a lesion that was identical clinically and histologically with the primary lesion at the end of four weeks. Although this disorder involves the skin primarily, the slight elevation in -globulin level observed may be a reflection of its systemic pathogenesis.

Author Affiliations
PHILADELPHIA

From the Department of Dermatology, School of Medicine, University of Pennsylvania.

Footnotes
Accepted for publication March 8, 1965.

Reprint requests to Department of Dermatology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia 19104.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?