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Nevus Angiolipomatosus Vs Focal Dermal Hypoplasia
J. B. HOWELL, MD
Arch Dermatol. 1965;92(3):238-248.
Abstract
Widespread linear hamartoma of vascular, elastic, adipose, and connective tissue was observed in two girls with another and opposite defect, that of failure of development of focal areas of dermis. No abnormality in number or chromosones was found. Multiple associated defects of development of mesodermal and ectodermal tissues were present. The fat tissue appeared to be associated with vascular proliferation in the papillary bodies and to crowd out the corium by downward infiltration of newly developed fat. Elastic tissue fibers were demonstratable crossing between the fat cells and were prominent in the superficial dermis. There was a definite stratum of dermis dividing the superficial nevus fat and the normal subcutaneous fat. This evidence justifies the explanation of the superficial fat tumors as nevoid neoplasms rather than herniations of subcutaneous fat.
Author Affiliations
DALLAS
Footnotes
Accepted for publication April 19, 1965.
Read before the meeting of the American Dermatological Association, Boca Raton, Fla, Feb 25 to March 2, 1965.
Reprint requests to 1719 Pacific, Dallas, Tex 75201 (Dr. Howell).
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