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Porphyria Cutanea Tarda Symptomatica (PCT-S)A Study of the Effect of Phlebotomy Therapy
JOHN H. EPSTEIN, MD;
ALLAN G. REDEKER, MD
Arch Dermatol. 1965;92(3):286-290.
Abstract
The effect of phlebotomy therapy on porphyrin metabolism was evaluated in five patients with porphyria cutanea tarda symptomatica (PCT-S). The removal of 2,500 to 4,500 cc over a three to four and one-half month period resulted in a marked reduction in urine and fecal uroporphyrin excretion in three of the subjects. Clinical improvement accompanied the chemical response in each case. In one patient, the induced chemical and clinical remission has persisted for six months without further treatment.
Author Affiliations
SAN FRANCISCO AND LOS ANGELES
From the Division of Dermatology, Department of Medicine, University of California School of Medicine, San Francisco (Dr. Epstein); the Department of Medicine, University of Southern California, Los Angeles; and the John Wesley County Hospital, Los Angeles (Dr. Redeker).
Footnotes
Accepted for publication May 14, 1965.
Presented at the 85th Annual Meeting of the American Dermatological Association, Boca Raton, Fla.
Reprint requests to Division of Dermatology, University of California, San Francisco Medical Center, San Francisco, Calif 94122 (Dr. Epstein).
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