This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (45)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

II. Histological and Histochemical Studies of Cutaneous Lesions

EDWARD S. PETERKA, MD; ROBERT M. FUSARO, MD; ROBERT W. GOLTZ, MD

Arch Dermatol. 1965;92(4):357-361.

Abstract
Histological and histochemical studies on specimens of skin from four patients with erythropoietic protoporphyria, whose lesions consisted of thickened eczematized plaques on sunlight exposed areas, showed that with hematoxylin and eosin staining large amounts of hyaline material invariably surrounded the blood vessels of the upper corium.

Histochemical studies indicated that this material contains an acidic carbohydrate-protein-lipid complex which includes an acid mucopolysaccharide.

Skin from a covered area appeared normal clinically and histologically.

This material may possibly arise from combination of degradation products of protoporphyrin and components of perivascular connective tissue. When an eruption is present on patients suspected of having erythropoietic protoporphyria, diagnostic help may be obtained by cutaneous biopsy.

Author Affiliations
MINNEAPOLIS

From the Division of Dermatology, University of Minnesota Medical School, Minneapolis.

Footnotes
Accepted for publication June 29, 1965.

Reprint requests to Division of Dermatology, University of Minnesota Medical School, Minneapolis, Minn (Dr. Peterka).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Childhood Porphyrias
Ahmed
Mayo Clin Proc. 2002;77:825-836.
ABSTRACT  

Erythropoietic Protoporphyria: A Clinical Study Based on 29 Cases in 14 Families
Schmidt et al.
Arch Dermatol 1974;110:58-64.
ABSTRACT  

Cutaneous Changes in the Porphyrias: A Microscopic Study
Epstein et al.
Arch Dermatol 1973;107:689-698.
ABSTRACT  

Lipoid Proteinosis and Erythropoietic Protoporphyria: A Histological and Histochemical Study
van der Walt and Heyl
Arch Dermatol 1971;104:501-507.
ABSTRACT  

HOUSTON DERMATOLOGICAL SOCIETY
Arch Dermatol 1969;100:374-383.
ABSTRACT  

Erythropoietic Protoporphyria: An Unusual Variant Reacting Abnormally in the Erythema Spectrum
Stern et al.
Arch Dermatol 1969;99:730-733.
ABSTRACT  

Visceral Involvement in Lipoid Proteinosis
Caplan
Arch Dermatol 1967;95:149-155.
ABSTRACT  

Erythropoietic Protoporphyria (Antea Lipoid Proteinosis) in Sisters: A Therapeutic Trial With Adenosine Monophosphate
CRIPPS
Arch Dermatol 1966;94:682-686.
ABSTRACT