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LOWELL A. JOHNSON, MD; R. K. WINKELMANN, MD

Arch Dermatol. 1965;92(6):621-624.

Abstract
Twenty-one children having atopic dermatitis, underwent skin tests with 1:1,000 methacholine; 16 demonstrated the delayed-blanch phenomenon. Seven were studied for skin temperature responses and compared with seven nonatopic children. Atopic children have a lower basal skin temperature than nonatopic children. Exposure to a cold environment produced more rapid cooling of the fingers and toes of the atopic children. Some alterations in cutaneous vascular responsiveness are present to development of severe dermatitis.

Author Affiliations
ROCHESTER, MINN

From the Section of Dermatology, Mayo Clinic and Mayo Foundation.

Footnotes
Accepted for publication July 23, 1965.

Reprint requests to Section of Publications, Mayo Clinic, Rochester, Minn 55902.

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