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Localized ArgyriaII. Chemical Nature of the Silver Containing Particles
WILLIAM R. BUCKLEY, MD;
CARL F. OSTER;
DAVID W. FASSETT, MD
Arch Dermatol. 1965;92(6):697-705.
Abstract
The use of chemical solubility techniques in association with electron microscopy as a method of detecting silver and its compounds, or both in skin tissue has been reported. It was possible to determine that the silver containing particles in the case of localized argyria were silver sulfide. Moreover, the particles were present chiefly intracellularly, nucleated to the margin of oval structures or densely packed within such structures. The average size of the silver sulfide particles was 300 Angstrom units with a calculated mass of 1.035 x 10-16 grams.
Author Affiliations
ROCHESTER, NY
From the University of Rochester School of Medicine and Dentistry, Strong Memorial Hospital, and Eastman Kodak Company.
Footnotes
Accepted for publication July 29, 1965.
Reprint requests to Eastman Kodak Company, Kodak Park Works, Rochester, NY 14604 (Dr. Buckley).
"Localized Argyria: I. Chemical Nature of the Silver Containing Particles" may be found in Archives of Dermatology 88:531-539, 1963.
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