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Carrier Specificity of Tuberculin-Type Reaction to Trivalent Chromium
HAIM A. COHEN, MD
Arch Dermatol. 1966;93(1):34-40.
Abstract
Forty-four patients suffering from contact dermatitis due to chromates gave positive tuberculin-type reactions to chromium chloride, free or bound. These reactions lasted two to six weeks.
Out of 20 patients suffering from contact dermatitis to bichromates who were injected with chromium chloride bound to human  -globulin, eight reacted positively. This may indicate that the tuberculin-type reaction to chromium chloride is a carrier-dependent sensitivity; these patients may be suffering from a partial autosensitization. Those patients who reacted positively to chromium -globulin were either clinically in a state of exacerbation or had a tendency to disseminate, or both.
Patients suffering from various skin diseases and skin sensitivities not due to chromates reacted negatively to intradermal injections of chromium chloride, free or in the form of complexes.
Author Affiliations
JERUSALEM, ISRAEL
From the Department of Dermatology and Venerology, Hadassah-University Hospital and Hebrew University Medical School.
Footnotes
Accepted for publication Aug 6, 1965.
Reprint requests to Department of Dermatology and Venerology, Hadassah-University Hospital, PO Box 499, Jerusalem, Israel.
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