This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Presence of Complement Fixing Antibodies to Corynebacterium acnes in the Sera of Patients With Acne Vulgaris

S. M. PUHVEL, PhD; I. K. HOFFMAN, MD; T. H. STERNBERG, MD

Arch Dermatol. 1966;93(3):364-366.

Abstract
Sera from 25 patients with varying degrees of acne vulgaris and sera from 23 patients without acne were tested for antibody levels to Corynebacterium acnes using the complement-fixation test. Results indicate that levels of complement-fixing antibodies to C acnes are significantly higher in patients with acne than in control groups. Antigen prepared from disrupted C acnes was found to be reactive in the complement-fixation test.

Author Affiliations
LOS ANGELES

From the Department of Medicine, Division of Dermatology, University of California Center for the Health Services, Los Angeles.

Footnotes
Accepted for publication Dec 15, 1965.

Reprint requests to School of Medicine, Division of Dermatology, University of California, Los Angeles 90024 (Dr. Puhvel).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Classic diseases revisited: Acne: a review of immunologic and microbiologic factors
Burkhart et al.
Postgrad. Med. J. 1999;75:328-331.
ABSTRACT | FULL TEXT  

Therapy for Acne Vulgaris
Leyden
NEJM 1997;336:1156-1162.
FULL TEXT  

Acne Vulgaris and Free Fatty Acids: A Review and Criticism
Voss
Arch Dermatol 1974;109:894-898.
ABSTRACT