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The Biological False-Positive Phenomenon in Elderly Men
RICHARD D. CARR, MD;
S. WILLIAM BECKER, MD;
CHARLES M. CARPENTER, MD
Arch Dermatol. 1966;93(4):393-395.
Abstract
Of 259 predominately elderly male patients, with a positive serologic test for syphilis, 162 had negative Treponema Pallidum Immobilization tests and were therefore biological false-positive (BFP) reactors. This represents a prevalence of BFP reactions which is 65 times greater than that found in the general population. There was no increased prevalence of collagen-vascular disease among elderly male BFP reactors. Venereal history was not helpful in differentiating the syphilitic from the BFP reactor. The physician was unable to differentiate accurately the latent luetic from the BFP reactor without aid of a specific treponemal antigen test.
Author Affiliations
COLUMBUS, OHIO; LONG BEACH, CALIF; LOS ANGELES
From the Department of Medicine, Division of Dermatology, Ohio State University College of Medicine, Columbus, Ohio (Dr. Carr); the Dermatology Section of the Department of Medicine, Veterans Administration Hospital. Long Beach, Calif (Dr. Becker); and the Department of Infectious Diseases of the University of California School of Medicine, Los Angeles (Dr. Carpenter).
Footnotes
Accepted for publication Dec 14, 1965.
Reprint requests to Ohio State University Hospitals, 320 W 10th Ave, Columbus, Ohio 43210 (Dr. Carr).
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
TESTS FOR SYPHILIS IN ELDERLY MEN
Wuepper and Tuffanelli
Arch Dermatol 1966;94:527-527.
ABSTRACT
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