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Lymphoma-like Presentation of Kaposi's SarcomaThree Cases Without Characteristic Skin Lesions
ARKADI M. RYWLIN, MD;
LOUIS RECHER;
ERWIN P. HOFFMAN, MD
Arch Dermatol. 1966;93(5):554-561.
Abstract
Three adults with Kaposi's sarcoma of the lymph nodes showed a clinical picture simulating a malignant lymphoma or a granulomatous disease in the absence of characteristic skin lesions. Fever, weight loss, lymphadenopathy, hepatosplenomegaly, anemia, and hypergammaglobulinemia were the presenting features. Monocytes were increased in the blood and plasma cells in the bone marrow.
The occurrence of a nodular pattern suggestive of follicular lymphoma is stressed among the gross findings in the involved lymph nodes. The microscopic features diagnostic of Kaposi's sarcoma consisted of a peripherally located, vascular spindle-celled tissue and of a more centrally placed, nodular, angiomatous proliferation of vascular channels with rare spindle cells. The accompanying, nonspecific lymph node lesions included a highly vascular follicular hyperplasia and an infiltration with plasma cells. The latter findings may lead to an erroneous diagnosis of plasmacytoma or chronic inflammation.
Author Affiliations
MIAMI, FLA
From the University of Miami School of Medicine, Mount Sinai Hospital (Drs. Rywlin and Hoffman) and Jackson Memorial Hospital (Dr. Recher), Miami, Fla.
Footnotes
Accepted for publication Jan 10, 1966.
Reprint requests to 4300 Alton Rd, Miami Beach, Fla 33140 (Dr. Rywlin).
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