This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (12)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

FREDERICK G. ZAK, MD; MAGDA MARTINEZ, MD; ARNOLD L. STATSINGER, MD

Arch Dermatol. 1966;93(6):674-678.

Abstract
Pale cell acanthoma, an entity recently established by French investigators, is characterized by a lesion, usually solitary, and commonly on the lower extremities of adults. The appearance is that of a round, reddish, elevated, occasionally bleeding, or crusted growth not larger than 20 mm, but often smaller. If untreated it has been known to remain for as long as 25 years. Treatment is surgical. Recurrences are unknown.

The microscopic appearance is unique and reveals regular acanthosis with striking pale prickle cells, rich in glycogen, and edematous vascularized papillae. A sprinkling of various inflammatory cells in dermis and epidermis and parakeratosis are noted with regularity. A sharp border between normal and abnormal epidermis is typical. Six pertinent cases are recorded, two of which have been followed for ten and three years respectively.

Author Affiliations
NEW YORK

From the departments of pathology, New York Medical College, Flower and Fifth Avenue Hospitals, New York, and Wycoff Heights Hospital, Brooklyn.

Footnotes
Accepted for publication Jan 10, 1965.

Reprint requests to Flower and Fifth Ave Hospital, 106th St at Fifth Ave, New York 10029 (Dr. Zak).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Clinical Recognition of Clear-Cell Acanthoma (Degos')
Fine and Chernosky
Arch Dermatol 1969;100:559-563.
ABSTRACT