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General and Regional Studies

HUBERT V. MOSS, MD; A. JARRELL RAPER, MD; WILLIAM SHAPIRO, MD; W. KENNETH BLAYLOCK, MD

Arch Dermatol. 1966;94(5):542-544.

Abstract
Forearm blood flows were determined in 11 patients with widespread inflammatory skin disease before and after therapy. Cardiac output was determined in ten patients before treatment and was again determined in four patients after therapy.

Forearm blood flows before treatment averaged 8.5 ml/min/100 gm of tissue and dropped to 4 ml/min/100 gm of tissue after therapy.

Cardiac outputs were normal in nine out of ten patients. All four patients studied after treatment showed a decrease in cardiac output.

The apparent increased skin blood flow in widespread erythrodermic skin disease seems to be critical only in patients with borderline cardiac function. The risk of high-output cardiac failure can be minimized by prompt and adequate treatment of the skin disease.

Author Affiliations
RICHMOND, VA

From the Department of Medicine, Division of Dermatology, Medical College of Virginia, Richmond. Dr. Shapiro is now at Southwestern Medical School, Dallas.

Footnotes
Accepted for publication July 18, 1966.

Read before the Section on Dermatology at the 115th Annual Meeting of the American Medical Association, Chicago, June 28, 1966.

Reprint requests to Division of Dermatology, Medical College of Virginia, Richmond (Dr. Blaylock).

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