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Erythema Multiforme Bullosum Caused by 9-Bromofluorene
CHARLES P. DeFEO, JR., MD
Arch Dermatol. 1966;94(5):545-551.
Abstract
College students in an organic chemistry laboratory preparing 9-bromofluorene from N-bromosuccinimide and fluorene developed erythema multiforme bullosum. This reaction took place 9 to 21 days following exposure in 24 of the 250 students who performed the experiment. The dermatitis began on exposed areas but rapidly involved covered portions of the body. Initially there were classical target lesions which coalesced leaving large denuded areas. Those affected developed elevated temperatures but were not particularly ill.
Author Affiliations
NEW YORK
From the Department of Dermatology, New York University Schools of Medicine, Misercordia Hospital, Lenox Hill Hospital, and St. Clare's Hospital, New York.
Footnotes
Accepted for publication June 17, 1966.
Read before the American Dermatological Association, Hot Springs, Va, April 14, 1966.
Reprint requests to 140 East 54th St, New York 10022.
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