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CARMELO SCARPA, MD; E. FERREA, MD

Arch Dermatol. 1966;94(5):589-591.

Abstract
By studying a group of patients examined during the last nine years at the Dermatology Clinic of the State University of Rome, it has been possible to verify a statistically significant decrease in the percentage of patients reactive to patch tests of aniline, paraphenylenediamine (PPDA), and procaine hydrochloride, during the last three-year period, 1962 to 1965, with respect to the previous three-year periods, 1956 to 1959 and 1959 to 1962.

Cobalt sensitivity showed a marked increase during the period 1959 to 1962 followed by a return to baseline levels.

Substantial variations in sensitivity to nickel and, probably, also potassium bichromate were not demonstrable over a similar time period.

Author Affiliations
ROME

From the Dermatology Department, State University of Rome.

Footnotes
Accepted for publication Aug 3, 1966.

Reprint requests to University of Rome Medical School, Clinica Dermatologica, Rome, Italy (Dr. Scarpa).

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