This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (56)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Differentiating Features of Conditions With Constriction of Digits

RICHARD C. GIBBS, MD; SAMUEL B. FRANK, MD

Arch Dermatol. 1966;94(5):619-625.

Abstract
A patient with keratoma hereditaria multilans (KHM), a young white girl, presented the following classic features of this rare disease: familial palmar and plantar hyperkeratosis beginning early in life, starfish-like keratoses of the dorsa of hands and feet, linear keratoses of elbows and knees, and constriction of digits beginning in the teens. A classification of the hereditary and nonhereditary diseases which exhibit digital constriction is briefly presented. The majority of the hereditary diseases with digital constriction have palmar and plantar hyperkeratosis, whereas the nonhereditary conditions are usually not keratotic.

In addition to the usual KHM findings our patient presents a high-frequency hearing loss; an unusual, pseudopelade-type alopecia; and transient, plantar bullae.

The disease is probably a variant of mal de Meleda.

Author Affiliations
NEW YORK

From the Department of Dermatology, New York University Schools of Medicine, New York.

Footnotes
Accepted for publication July 12, 1966.

Reprint requests to 15 Park Ave, New York 10016 (Dr. Gibbs).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Molecular Quantification of Human {beta}-Glucuronidase Levels in a Patient with Vohwinkel's Syndrome
Hughes et al.
J. Am. Podiatr. Med. Assoc. 2001;91:114-120.
ABSTRACT | FULL TEXT  

Clinical and Genetic Studies of 3 Large, Consanguineous, Algerian Families With Mal de Meleda
Bouadjar et al.
Arch Dermatol 2000;136:1247-1252.
ABSTRACT | FULL TEXT  

Linkage of an American Pedigree With Palmoplantar Keratoderma and Malignancy (Palmoplantar Ectodermal Dysplasia Type III) to 17q24: Literature Survey and Proposed Updated Classification of the Keratodermas
Stevens et al.
Arch Dermatol 1996;132:640-651.
ABSTRACT  

Congenital Ichthyosiform Dermatosis With Linear Keratotic Flexural Papules and Sclerosing Palmoplantar Keratoderma
Pujol et al.
Arch Dermatol 1989;125:103-106.
ABSTRACT  

Variant of Keratoderma Hereditaria Mutilans (Vohwinkel's Syndrome) Treatment With Orally Administered Isotretinoin
Camisa and Rossana
Arch Dermatol 1984;120:1323-1328.
ABSTRACT  

Successful Treatment of Keratoderma Hereditaria Mutilans With an Aromatic Retinoid
Pang et al.
Arch Dermatol 1981;117:225-228.
ABSTRACT  

Acral Keratoderma
Nesbitt et al.
Arch Dermatol 1975;111:763-768.
ABSTRACT  

Pseudoainhum Constricting Bands of the Extremities
Raque et al.
Arch Dermatol 1972;105:434-438.
ABSTRACT  

Congenital Hyperkeratoses in Africans
Verhagen and Koten
Arch Dermatol 1968;98:364-371.
ABSTRACT