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The Basement Membrane in Relation to Carcinoma of the Skin
EDWARD P. CAWLEY, MD;
Y. T. HSU, MD;
PEYTON E. WEARY, MD
Arch Dermatol. 1966;94(6):712-715.
Abstract
The histochemically demonstrable basement membrane marking the epidermaldermal junction is usually normal in the epidermal carcinomas in situ, whereas in the invasive epidermoid carcinomas it is, in most instances, severely disrupted. However, nests of invading cells and metastatic foci in lymph nodes may show basement membranes, so that presence or absence of the structure is not an absolute criterion for invasiveness.
Author Affiliations
CHARLOTTESVILLE, VA
From the Department of Dermatology and the Department of Pathology, University of Virginia School of Medicine, Charlottesville, Va.
Footnotes
Accepted for publication Sept 7, 1966.
Reprint requests to Department of Dermatology, University of Virginia School of Medicine, Charlottesville, Va (Dr. Cawley).
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ABSTRACT
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