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Allergic Vasculitis Gougerot-Ruiter SyndromeImmunofluorescent Study
S. G. STRINGA, MD;
C. BIANCHI, MD;
A. M. CASALA, MD;
O. BIANCHI, MD
Arch Dermatol. 1967;95(1):23-27.
Abstract
The immunofluorescent technique was used to determine the presence of immuno- -globulin (IgG) and complement (C'3) in allergic vasculitis (AV) skin lesions. By the use of specific antisera it was possible to demonstrate that IgG and C'3 are present in the areas of fibrinoid necrosis of capillaries and small vessels in the corium. The presence of IgG and complement and the absence of other plasma proteins suggest that an immunologic process is taking place in the pathogenesis of AV. Similarity between these findings and those demonstrated in experimentally-induced Arthus phenomenon has been considered.
Author Affiliations
BUENOS AIRES
From the departments of dermatology of the Instituto de Investigaciones Médicas, Hospital Tornú (Dr. Stringa), and the Policlínico de Avellaneda (Drs. C. Bianchi, Casala, and O. Bianchi), Buenos Aires.
Footnotes
Accepted for publication Sept 9, 1966.
Read before the Second Annual Dermatology Research Meeting of the Asociacion Argentina de Dermatologia, Buenos Aires, Nov 20, 1965.
Reprint requests to Sante Fe 3044 2P, Buenos Aires (Dr. Casala).
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