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The Scalded Skin Syndrome in Small Children
Edmund D. Lowney, PhD, MD;
Joseph V. Baublis, MD;
George M. Kreye, MD;
E. Richard Harrell, MD;
Albert R. McKenzie, MD
Arch Dermatol. 1967;95(4):359-369.
Abstract
The scalded skin syndrome, or toxic epidermal necrolysis of Lyell, is a nonspecific reaction pattern of the skin. In small children, the syndrome has been associated with group 2 staphylococcal infection, as has previously been described in Ritter's disease. We have observed this association in four children. Other cases of scalded skin syndrome are almost certainly due to drugs. Other infectious and toxic agents are also occasionally responsible for the syndrome.
Although the scalded skin syndrome may be lethal to infants less than 1 year of age, children between 1 and 6 years of age usually recover rapidly, exhibiting a mortality of only 7%. In patients 6 or more years of age, the syndrome is fatal more than 40% of the time.
Author Affiliations
Ann Arbor, Mich
From the departments of dermatology and pediatrics, University of Michigan Medical School, Ann Arbor. Dr. McKenzie is now at the US Naval Academy, Annapolis, Md.
Footnotes
Accepted for publication Jan 31, 1967.
Reprint requests to Department of Dermatology, University Hospital, Ann Arbor, Mich 48104 (Dr. Lowney).
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