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A Report of a Case and Review of the Literature

L. Stankler, MB, ChB, MRCPG; G. Leslie, MD

Arch Dermatol. 1967;95(5):509-513.

Abstract
A patient with generalized granuloma annulare is described. The eruption was restricted to exposed sites.

Forty-seven cases from the literature are reviewed. The clinical appearance may be confused with lichen planus, sarcoidosis, tuberculosis cutis, and lichen myxedematosus. The histology is variable and collagenous; cellular or vascular changes may occur separately or in combination. Treatment with gold injections, antihistamines, x-ray therapy, and bismuth have not been consistently effective. Claims for improvement with diethylstilbestrol, systemic corticosteroids, and penicillin have been made but these are difficult to assess because of the variable course of the disease. Antimalarials may be of value.

Author Affiliations
Glasgow, Scotland

From the Department of Dermatology, Royal Infirmary, Glasgow, Scotland.

Footnotes
Accepted for publication Feb 21, 1967.

Reprint requests to Department of Dermatology, Wards 20-21, Royal Infirmary, Glasgow C4, Scotland (Dr. Stankler).

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