This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Custom-Made Topical Corticosteroid

Erwin H. Zimmerman, MD

Arch Dermatol. 1967;95(5):514-519.

Abstract
Betamethasone 17-valerate, a new corticosteroid synthesized expressly for topical use, was clinically evaluated in the treatment of various dermatoses in a two-part study. In the first part, a clinical-use study, betamethasone 17-valerate 0.1% cream produced excellent to good results in 139 (84%) of 166 patients. In the second part, a double-blind, bilateral, symmetrical paired comparison, betamethasone 17-valerate 0.05% ointment proved superior to the other corticosteroid in 37 (69%) of 54 patients, and the two were equally efficacious in 16 (29%). With the exception of two patients who developed local irritation, no gross evidence of systemic absorption or other adverse effects was noted.

Author Affiliations
Huntington, NY

Footnotes
Accepted for publication Nov 8, 1966.

Reprint requests to Huntington Medical Arts Center, 23 Green St, Huntington, NY (Dr. Zimmerman).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?