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Skin Tests With Nuclear Factors in Systemic Lupus Erythematosus
Henry E. Jones, MD;
Vincent J. Derbes, MD;
Oren B. Gum, MD, PhD;
Faris J. Azoury, MD
Arch Dermatol. 1967;95(6):559-564.
Abstract
Intradermal testing was carried out on 22 patients with systemic lupus erythematosus (SLE) using homologous leukocytes, nucleoprotein, histone, and deoxyribonucleic acid. Ten patients with positive reactions to DNA had acute lupus and lupus nephritis confirmed by biopsy. Sera from nine of ten of these patients were tested for antinuclear factors (ANF) by the immunofluorescent technique, and the shaggy and homogeneous patterns were exhibited by all.
Author Affiliations
New Orleans
From the Department of Medicine, Section of Allergy-Dermatology (Drs. Jones and Derbes) and of Arthritis (Dr. Gum), Tulane University School of Medicine, New Orleans, and the Department of Medicine, Section of Rheumatology (Dr. Azoury), Wayne State University College of Medicine, Detroit.
Footnotes
Accepted for publication Feb 8, 1967.
Read before the meeting of the American Dermatological Association, Hot Springs, Va, April 14-19, 1966.
Reprint requests to Department of Medicine, Section of Allergy-Dermatology, Tulane University School of Medicine, New Orleans 70112 (Dr. Derbes).
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ABSTRACT
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