This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (73)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Histological, Histochemical, and Electron Microscopic Studies

Ken Hashimoto, MD; Richard J. DiBella, MD; Gregory M. Borsuk, MD; Walter F. Lever, MD

Arch Dermatol. 1967;96(5):500-519.

Abstract
Eruptive hidradenoma, a rare type of syringoma, was studied histologically, histochemically, and electron microscopically in two patients. In spite of its peculiar clinical differences, such as occurrence of numerous lesions with limited distribution to anterior surfaces of the body, it showed features identical to the eyelid type syringoma. Direct connections were found between the lesions and epidermis and between individual lesions, but not between the lesions and underlying eccrine secretory segments. Also, cystic or tubular spaces were lined with an "immature eccrine intra-epidermal type" of epithelium which possessed a periluminal tonofilament band, lysosomes, keratohyaline granules, and often underwent complete keratinization. No secretory epithelium was found in the lesion. Dermal histiocytes with typical Langerhans cell granules and collagen fiber bundles were seen in parenchyma. It seemed that the lesion was undergoing constant destruction and regeneration.

Author Affiliations
Boston

From the Department of Dermatology, Tufts University School of Medicine, and the Dermatology Research Laboratories, New England Medical Center Hospitals, and Boston City Hospital, Boston.

Footnotes
Accepted for publication June 28, 1967.

Reprint requests to 171 Harrison Ave, Boston 02111 (Dr. Hashimoto).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

An Eruption of Asymptomatic Brown Papules
Beers
Arch Dermatol 1990;126:957-958.
ABSTRACT  

Eruptive Syringoma
Pruzan et al.
Arch Dermatol 1989;125:1119-1120.
ABSTRACT  

Eruptive Pruritic Papules
Kuttner et al.
Arch Dermatol 1989;125:985-986.
ABSTRACT  

Familial Syringoma: Case History and Application of Monoclonal Anti-Eccrine Gland Antibodies
Hashimoto et al.
Arch Dermatol 1985;121:756-760.
ABSTRACT  

Eruptive Generalized Clear Cell Syringomas
Diestelmeier and Rodman
Arch Dermatol 1983;119:927-929.
ABSTRACT  

Eruptive Syringomas in Down's Syndrome
Urban et al.
Arch Dermatol 1981;117:374-375.
ABSTRACT  

Syringoma Localized to the Vulva
Thomas et al.
Arch Dermatol 1979;115:95-96.
ABSTRACT  

Dermal Duct Tumor: A Histochemical and Electron Microscopic Study
Hu et al.
Arch Dermatol 1978;114:1659-1664.
ABSTRACT  

Acral Syringoma
Hughes and Apisarnthanarax
Arch Dermatol 1977;113:1435-1436.
ABSTRACT  

Syringoma of the Vulva
Carneiro et al.
Arch Dermatol 1971;103:494-496.
ABSTRACT  

Histogenesis of Skin Appendage Tumors
Hashimoto and Lever
Arch Dermatol 1969;100:356-369.
ABSTRACT  

Some New Aspects of the Langerhans Cell
Hashimoto and Tarnowski
Arch Dermatol 1968;97:450-464.
ABSTRACT