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Arch Dermatol. 1998;134:1286-1288.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

THE REPORT by Coven et al¹ in this issue of the ARCHIVES contains some interesting information on a possible mechanism of action of psoralen–UV-A (PUVA) therapy in the treatment of psoriasis and some limited data on the efficacy of trimethylpsoralen (TMP) bath PUVA therapy. The authors conclude that in comparison with conventional PUVA therapy (oral administration of methoxsalen followed by UV-A radiation), "we believe that TMP bath PUVA therapy represents a sensible alternative for the present." This conclusion raises the obvious question: a sensible alternative for whom? For the physician in an investigative laboratory of a large university and/or the dermatologist in a solo practice far removed from such an academic environment? Rather than answering this question directly it is perhaps timely to evaluate the safety, efficacy, and appropriateness of the various alternatives to conventional PUVA therapy that have been advocated and are used.

BATH PUVA THERAPY

The term bath PUVA therapy is . . . [Full Text of this Article]

SOAK PUVA THERAPY

TOPICAL PUVA THERAPY

DO-IT-YOURSELF PUVA THERAPY

CONCLUSIONS

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Trimethylpsoralen Bath PUVA Is a Remittive Treatment for Psoriasis Vulgaris: Evidence That Epidermal Immunocytes Are Direct Therapeutic Targets
Todd R. Coven, Frank P. Murphy, Patricia Gilleaudeau, Irma Cardinale, and James G. Krueger
Arch Dermatol. 1998;134(10):1263-1268.
ABSTRACT | FULL TEXT