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Zoltán Trizna, MD, PhD; Jaime Tschen, MD; Ethan A. Natelson, MD
St Joseph Hospital, Houston, Tex

Arch Dermatol. 1998;134:1477-1482.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 75-year-old white man with a 4-year history of chronic myeloproliferative disease suddenly began vomiting and had generalized bone pain, weakness, and a temperature of 38°C. Physical examination revealed that he had more than 50 white, nontender, moderately firm, subcutaneous nodules, measuring 5 to 25 mm in diameter, on the chest wall, abdomen, back, and extensor surface of the left leg (Figure 1 and Figure 2). There were several ecchymoses on the left shoulder and arm. No lesions were observed on the mucous membranes. A 3-mm punch biopsy specimen was sent for histopathological examination (Figure 3 and Figure 4).

Figure 1.

Figure 2.

Figure 3.

Figure 4.

What is your diagnosis?

Diagnosis: Leukemia cutis.

Histologic examination revealed dense leukemic infiltration of the dermis by immature cells, with occasional mitoses.

It is important to review our patient's history. He . . . [Full Text of this Article]

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