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Multiple Subcutaneous Nodules on the Torso and Leg
Zoltán Trizna, MD, PhD;
Jaime Tschen, MD;
Ethan A. Natelson, MD
St Joseph Hospital, Houston, Tex
Arch Dermatol. 1998;134:1477-1482.
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REPORT OF A CASE
A 75-year-old white man with a 4-year history of chronic myeloproliferative disease suddenly began vomiting and had generalized bone pain, weakness, and a temperature of 38°C. Physical examination revealed that he had more than 50 white, nontender, moderately firm, subcutaneous nodules, measuring 5 to 25 mm in diameter, on the chest wall, abdomen, back, and extensor surface of the left leg (Figure 1 and Figure 2). There were several ecchymoses on the left shoulder and arm. No lesions were observed on the mucous membranes. A 3-mm punch biopsy specimen was sent for histopathological examination (Figure 3 and Figure 4).
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Figure 1.
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Figure 2.
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Figure 3.
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Figure 4.
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What is your diagnosis?
Diagnosis: Leukemia cutis.
Histologic examination revealed dense leukemic infiltration of the dermis by immature cells, with occasional mitoses.
It is important to review our patient's history. He . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Subcutaneous Myeloid Sarcoma
Geyer et al.
Arch Dermatol 2005;141:104-106.
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