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Viliam Filo, MD; Stefan Galbavy, MD; Juraj Pec, MD
University Hospitals, Bratislava and Martin, Slovakia.

Arch Dermatol. 1998;134:1627-1632.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 19-year-old man presented with a 2- to 3-week history of a pink, slightly painful tumor on the helix of the left ear. Physical examination revealed a solitary, dome-shaped, reddish pink, 7-mm-diameter lesion that was slightly umbilicated and crusted (Figure 1). The preliminary diagnosis was keratoacanthoma. Excisional biopsy of the tumor was performed. The histologic findings are shown in Figure 2. Staining with antibodies to S100 protein is shown in Figure 3.

Figure 1.

Figure 2.

Figure 3.

What is your diagnosis?

Diagnosis: Spitz nevus (SN).

Histopathologic examination showed epidermal acanthosis and nests of large, predominantly spindle cell–shaped melanocytes at the dermoepidermal junction and in the dermis (Figure 2). Some of the cells demonstrated mitotic activity. Atypical mitoses were not seen. Melanin pigment was absent.

The tumor nests were negative for anticytokeratin antibodies AE1 and AE3. They were also . . . [Full Text of this Article]

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