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I was interested to read the report of localized Darier disease (keratosis follicularis) by O'Malley and colleagues,¹ and I feel that it may be pertinent to add some recent information regarding a previously reported case of mine that these authors cite.²

My patient was a young woman with apparent unilateral Darier disease affecting the left side of her body; she had a typical rash with a wide distribution on the left side of the trunk and left arm and also unilateral palmar pits and the nail changes of Darier disease affecting several digits of the left hand and foot. On this basis, we proposed² that she had unilateral Darier disease rather than simply an acantholytic dyskeratotic epidermal nevus. This patient was recently investigated for pain in the right iliac fossa, possibly related to ovulation, and was demonstrated to have a benign, 2.5-cm cyst on her right ovary. During the course . . . [Full Text of this Article]

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