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Syringolymphoid hyperplasia with alopecia (SLHA) is a rare disease, which was first reported by Sarkany in 1969.¹ Clinical features of SLHA include hairless patches with follicular papules. Histopathologic characteristics include a dense lymphohistiocytic infiltrate surrounding hyperplastic eccrine sweat glands and ducts. We report the ninth case of SLHA. Genotypical analysis revealed a biallelic monoclonal rearrangement of the T-cell receptor chain gene. This rearrangement provides further evidence that SLHA represents a cutaneous T-cell lymphoma.

Report of a Case

A 52-year-old man with a 5-year history of an undetermined skin disease presented to the Department of Dermatology, Heinrich-Heine University, Düsseldorf, Germany. Results of a physical examination revealed multiple, disseminated, brownish scaly papules, giving the patient's feet a dyshidrosiform aspect (Figure 1). Additionally, he had erythematous lesions with papules on the lower part of his legs that showed complete alopecia. Biopsy specimens taken from the sole of his right foot and the lower part of . . . [Full Text of this Article]

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Cutaneous T-Cell Lymphoid Dyscrasia: A Unifying Term for Idiopathic Chronic Dermatoses With Persistent T-Cell Clones
Guitart and Magro
Arch Dermatol 2007;143:921-932.
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