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The Leukotriene Antagonist Zafirlukast as a Therapeutic Agent for Atopic Dermatitis
John A. Carucci, MD, PhD;
Kenneth Washenik, MD, PhD;
Alan Weinstein, MD;
Jerome Shupack, MD;
David E. Cohen, MD, MPH
From the New York University Medical Center, New York, NY.
Arch Dermatol. 1998;134:785-786.
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REPORT OF CASES
CASE 1
A 42-year-old man presented with a 10-year history of atopic dermatitis that was refractory to treatment with UV light, oral antihistamines, and high-potency topical corticosteroids. On presentation, he denied any other medical problems and was taking no medicines. His condition improved with the use of cyclosporine; however, this regimen was discontinued secondary to transaminitis due to hepatitis C infection, which was treated with interferon alfa. His atopic dermatitis flared after discontinuation of cyclosporine therapy. A physical examination showed erythroderma involving more than 70% of his body surface area approximately 2 weeks after cyclosporine therapy was discontinued.
CASE 2
A 61-year-old man presented with a lifelong history of atopic dermatitis. His condition did not improve with the use of high-potency topical corticosteroids and UV-B phototherapy. He had no other medical problems and was . . . [Full Text of this Article] CASE 3 CASE 4
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
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