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The Diagnostic Reproducibility of Melanocytic Dysplasia
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The otherwise carefully designed and executed study by Weinstock et al1 comes to conclusions that seem rather at variance with the objective data. According to the authors, "melanocytic dysplasia can be reproducibly graded among diverse general dermatopathologists." A review of the salient data suggests otherwise.
Their values for interobserver concordance in the diagnosis of melanocytic dysplasia are presented according to several different measures, a few of which will have little intuitive meaning for most of those who deal with issues of diagnostic reliability. For example, how much reliability is indicated by a mean intraclass correlation coefficient of 0.67? How about a statistic of 0.76? Or a range of Pearson product moment correlations from 0.67 to 0.84? On the other hand, rates of exact agreement among observers are readily understood. Weinstock et al1 report that for a 5-point rating scale (no dysplasia, slight dysplasia, moderate dysplasia, severe dysplasia, and melanoma) the . . . [Full Text of this Article]
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