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Nicotine for Pyoderma Gangrenosum
Ronni Wolf, MD
Maccabee Health Care Outpatient Clinic and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Vincenzo Ruocco, MD
Department of Dermatology, University of Naples II School of Medicine and Surgery, Naples, Italy
Arch Dermatol. 1998;134:1071-1072.
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REPORT OF A CASE
A 35-year-old man with no past medical illness developed bloody diarrhea with up to 12 loose stools per day and abdominal pain in February 1984. He had smoked 1 pack of cigarettes per day for 16 years until he stopped smoking 2 months prior to the onset of his illness. In March 1984, he was hospitalized because of toxic dilatation of the colon (toxic megacolon). Treatment consisted of intravenous fluids and electrolytes, broad-spectrum antibiotics, and corticosteroids. After the condition had slowly improved, he was released on a daily dosage of 40 mg of prednisone, 4 g of sulfasalazine, and 800 mg of cimetidine. Findings of colonoscopic and sigmoidoscopic examinations with biopsies were inconclusive, and he was diagnosed as having active nongranulomatous colitis similar to inflammatory bowel disease, without being able to differentiate between ulcerative colitis and Crohn disease. He subsequently had short remissions with . . . [Full Text of this Article]
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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A Case of Pemphigus Vulgaris Improved by Cigarette Smoking
Mehta and Martin
Arch Dermatol 2000;136:15-17.
FULL TEXT
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