Mohs Micrographic Excision of Lentigo Maligna Using Mel-5 for Margin Control
Edward A. Gross, MD;
William K. Andersen, MD;
Gary S. Rogers, MD
University of Miami School of Medicine, Miami Fla;
Boston University School of Medicine, Boston, Mass
Arch Dermatol. 1999;135:15-17.
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REPORT OF CASES
CASE 1
A 43-year-old man presented with a pigmented lesion on the left earlobe. Histologic evaluation of a biopsy specimen demonstrated lentigo maligna. The patient was referred to our institution for micrographic excision of the lesion.
CASE 2
A 56-year-old man presented with a pigmented lesion on the right preauricular cheek. A biopsy specimen demonstrated lentigo maligna. The lesion was excised in a standard fashion with 0.5-cm margins. Histologic evaluation of the excised specimen showed persistence of the tumor at the surgical margin. A second attempt at excision failed to fully excise the tumor. The patient was referred to our institution for micrographic excision of the residual tumor.
THERAPEUTIC CHALLENGE
Successful micrographic excision of lentigo maligna is hindered by difficulty interpreting frozen sections stained with hematoxylin-eosin (HE).
SOLUTION
CASE 1
The lentigo maligna was excised using Mohs micrographic excision starting with 0.5-cm margins. In addition to HE . . . [Full Text of this Article] CASE 2
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Arch Dermatol 2004;140:1087-1092.
ABSTRACT
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