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Satoyoshi syndrome (SS) is a rare disorder of unknown cause characterized by progressive, painful, intermittent muscle spasms, diarrhea or unusual malabsorption, endocrinopathy with amenorrhea, secondary skeletal abnormalities, and especially alopecia areata. We report a case of SS and review the clinical features.

Report of a Case

A 24-year-old Japanese woman presented with symptoms of fever, abdominal pain, diarrhea, amenorrhea, and alopecia universalis (Figure 1). Intermittent muscle spasms of her whole body occurred several times per hour at irregular intervals.

Figure appears in full text version. Figure 1. A clinical feature of Satoyoshi syndrome is alopecia universalis, except for the eyelashes.

At age 4 years, she started losing her hair, and it progressed to alopecia totalis by about age 9 years. Since age 13 she had frequent abdominal pain and diarrhea. At age 20 she began to have the characteristic muscle spasms with fever and amenorrhea. Menstruation recently stopped for 6 months. Familial history was unremarkable.

The results of . . . [Full Text of this Article]

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

A Case of Satoyoshi Syndrome: A Multisystem Disorder
Kamat et al.
CLIN PEDIATR 2003;42:745-748.
ABSTRACT