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Malar Rash in a Child
Steven W. Spence;
Billie F. Cosgrove, MD;
Michael J. Ford, MD
University of Florida College of Medicine, Gainesville
Arch Dermatol. 1999;135:1267-1272.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 9-year-old boy presented for evaluation of a facial rash, which was made more prominent by sunlight and stress (Figure 1). The rash first appeared 4 years before referral, shortly after a hospital admission for pneumococcal meningitis. The patient had never complained of constitutional symptoms. His medical history was significant for many episodes of sinusitis, pharyngitis, and otitis media. His sister also had chronic sinusitis and a history of pneumococcal meningitis. Physical examination showed large, scaly erythematous plaques in a malar distribution and no other skin findings. We obtained a punch biopsy specimen from the right cheek (Figure 2).
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Figure 1.
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Figure 2.
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What is your diagnosis?
Diagnosis: Hereditary C2 deficiency with associated cutaneous lupus erythematosus and pyogenic infections.
The biopsy specimen displayed minimal hyperkeratosis with mild focal basilar vacuolopathy and rare necrotic keratinocytes, as well as an angiocentric, mixed-cell, superficial inflammatory infiltrate consisting of lymphocytes, occasional . . . [Full Text of this Article]
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