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Treatment of Refractory Disseminated Mycobacterium abscessus Infection With Interferon Gamma Therapy
Arthur S. Colsky, PhD, MD;
Andrew Hanly, MD;
George Elgart, MD;
Fransisco A. Kerdel, MD
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Fla
Arch Dermatol. 1999;135:125-127.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 60-year-old woman was admitted to the hospital with disseminated Mycobacterium abscessus infection. Her disease had been refractory to conventional antibiotic therapy and she continued to develop painful suppurating abscesses on her trunk and extremities. Her infection followed treatment for essential thrombocytosis, which was diagnosed in September 1993. For this, she initially was treated unsuccessfully with hydroxyurea (Hydrea) and plateletpheresis. She was then treated with phosphorus P 32 and busulfan, which was complicated by the development of a protracted pancytopenia with a white blood cell count at the lowest point of 0.0009x109/L. A bone marrow biopsy specimen showed mild myelodysplasia, and she was treated with filgrastim (Neupogen) and epoetin alfa (Epogen) over a several-month period, with eventual recovery of her blood cell counts to normal by May 1996. In December 1995, while . . . [Full Text of this Article]
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
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