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Martin Schaller, MD; Marc Heckmann, MD; Birgit Wörle, MD; Carl G. Schirren, MD
Ludwig-Maximilians-University, Munich, Germany

Arch Dermatol. 1999;135:203-208.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 51-year-old woman presented with a 6-month history of fatigue and a 5-month history of a sometimes painful and pruritic nonhealing nodule on her vulva that had not resolved despite electrodesiccation and oral antibiotic therapy. Physical examination showed an erythematous, ulcerated, 0.8-cm-diameter nodule on the right labium minus (Figure 1). Laboratory evaluation revealed the following results: hemoglobin, 80 g/L; platelets, 71.0 x 10⁹/L; total peripheral white blood cells, 6.5 x 10⁹/L, with 0.06 segmented neutrophils, 0.46 lymphocytes, 0.09 mononuclear cells, and 0.34 undifferentiated blast cells; serum VDRL test, nonreactive; and lactate dehydrogenase, 241 U/L. An excisional biopsy specimen of the nodule was obtained for histopathologic examination (Figure 2).

Figure 1.

Figure 2.

What is your diagnosis?

Diagnosis: Nodular herpes simplex virus (HSV) infection in a patient with myeloid leukemia.

Histologic examination revealed intraepidermal vesicles containing acantholytic cells and ulceration. There was ballooning degeneration of . . . [Full Text of this Article]

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