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Where Do We Go From Here?

Arch Dermatol. 1999;135:583-586.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

IN THIS issue of the ARCHIVES, Firooz et al¹ present some data on the validity of the U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis (AD),^2-4 which are based on the criteria of Hanifin and Rajka,⁵ in a sample of 416 patients of all ages attending a private dermatology clinic in Iran. Firooz et al¹ found a sensitivity and specificity of 10% and 98%, respectively, compared with the clinical diagnosis of one senior private dermatologist. The authors state that although the high specificity of the criteria makes them suitable for clinical trial work, the poor validity of the criteria in this study makes them unsuitable for epidemiological use. For example, if the validity indices of this study are true, then in a population setting in which the true prevalence of AD is 10%, the positive predictive value of the criteria (proportion of those with a positive test result who really . . . [Full Text of this Article]

ATTRIBUTES OF A GOOD VALIDATION STUDY FOR DIAGNOSTIC CRITERIA


USE THE CRITERIA QUESTIONS AND EXAMINATION PROTOCOL EXACTLY AS RECOMMENDED

ENSURE THAT TRANSLATION FOLLOWS A STRICT FORMAT

TEST THE CRITERIA IN THE SETTING IN WHICH THEY ARE INTENDED TO BE USED

ENSURE THAT THOSE ACTING AS ASSESSORS OR AS THE CLINICAL CRITERION STANDARD ARE BLINDED TO THE CRITERIA BEING TESTED

ENSURE THAT THE CLINICIAN WHO IS THE CLINICAL CRITERION STANDARD IS COMPARABLE TO OTHER CLINICIANS

WHERE DO WE GO FROM HERE?


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