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Sharon Horton, MD; Richard Mizuguchi, MD; Ali Moiin, MD; Ken Hashimoto, MD
Wayne State University, Detroit, Mich

Arch Dermatol. 1999;135:1113-1118.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 32-year-old white woman presented with a 2-year history of nail loss. She initially had noted a "small bump" on the corner of her right thumbnail. In time, the bump grew larger and split the nail, and, finally, a portion of the right thumbnail fell off. Occasionally, the patient experienced pain in the affected area of her thumb. Her medical history was noncontributory.

Cutaneous examination revealed a 7-mm erythematous nodule located on the lateral aspect of the right thumb, with the loss of one third of the lateral nail plate (Figure 1). An x-ray film of the thumb showed no evidence of bone abnormality. A biopsy specimen was obtained (Figure 2).

Figure 1.

Figure 2.

What is your diagnosis?

Diagnosis: Amelanotic subungual melanoma.

The surface epithelium was irregularly acanthotic, with extensive proliferation of atypical melanocytic cells at the . . . [Full Text of this Article]

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