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Susan Holmes; Mary Fallowfield; Pamela McHenry
University of Glasgow and Western Infirmary, Glasgow, Scotland

Arch Dermatol. 1999;135:1113-1118.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A previously healthy 84-year-old man presented with a 1-year history of a slowly growing nodular lesion on his left temple that would bleed when he experienced minor trauma. Clinical examination revealed a well-circumscribed, 2-cm, crusted, bluish-red, polypoid lesion (Figure 1) with no evidence of cervical lymphadenopathy. The results of the patient's physical examination and baseline laboratory investigations were otherwise unremarkable. An excisional biopsy specimen of the lesion with a 5-mm margin of normal tissue was obtained (Figure 2 and Figure 3).

Figure 1.

Figure 2.

Figure 3.

What is your diagnosis?

Diagnosis: Atypical fibroxanthoma (AFX) with osteoclastlike giant cells.

Low-power microscopic examination of the excised specimen revealed a polypoid well-circumscribed, nonencapsulated, highly cellular tumor in the dermis. The tumor extended up to the epidermis, which was somewhat attenuated but not ulcerated (Figure 2). Higher-power examination showed closely packed polygonal and plump spindle cells with eosinophilic cytoplasm . . . [Full Text of this Article]

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